Timothy K. Maclachlan: search on Z-Library

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1

Storm forecasting: additional lessons from the CD28 superagonist TGN1412 trial

Horvath, Christopher, Andrews, Laura, Baumann, Andreas, Black, Lauren, Blanset, Diann, Cavagnaro, Joy, Hastings, Kenneth L., Hutto, David L., MacLachlan, Timothy K., Milton, Mark, Reynolds, Theresa, R

Journal:

Nature Reviews Immunology

Year:

2012

Language:

english

File:

PDF, 118 KB

english, 2012

2

Deglacial history of glacial lake windermere, UK: implications for the central British and Irish Ice Sheet

Pinson, Luke J. W., Vardy, Mark E., Dix, Justin K., Henstock, Timothy J., Bull, Jonathan M., Maclachlan, Suzanne E.

Journal:

Journal of Quaternary Science

Year:

2013

Language:

english

File:

PDF, 912 KB

english, 2013

3

Cloning of murine CDK9/PITALRE and its tissue-specific expression in development

Luigi Bagella, Timothy K. MacLachlan, Russell J. Buono, M. Michele Pisano, Antonio Giordano, Antonio De Luca

Journal:

Journal of Cellular Physiology

Year:

1998

Language:

english

File:

PDF, 762 KB

english, 1998

4

Industry experiences with immune-mediated findings in biotherapeutic nonclinical toxicology studies

MacLachlan, Timothy K., Kronenberg, Sven, Marshall, Nikki, Andrews, Laura, Berens, Shawn Jay, Brouta, Frederic, Fogal, Birgit, Freebern, Wendy, Herzyk, Danuta, Kamperschroer, Cris, Kiessling, Andrea,

Journal:

Regulatory Toxicology and Pharmacology

Year:

2020

File:

PDF, 1.71 MB

2020

5

Post-proliferative cyclin E-associated kinase activity in differentiated osteoblasts: Inhibition by proliferating osteoblasts and osteosarcoma cells

Elisheva Smith, Baruch Frenkel, Timothy K. MacLachlan, Antonio Giordano, Janet L. Stein, Jane B. Lian, Gary S. Stein

Journal:

Journal of Cellular Biochemistry

Year:

1997

Language:

english

File:

PDF, 177 KB

english, 1997

6

Binding of CDK9 to TRAF2

Timothy K. MacLachlan, Nianli Sang, Antonio De Luca, Pier Lorenzo Puri, Massimo Levrero, Antonio Giordano

Journal:

Journal of Cellular Biochemistry

Year:

1998

Language:

english

File:

PDF, 228 KB

english, 1998

7

TRAF2 expression in differentiated muscle

Timothy K. MacLachlan, Antonio Giordano

Journal:

Journal of Cellular Biochemistry

Year:

1998

Language:

english

File:

PDF, 129 KB

english, 1998

8

“p53: Twenty Years On” in Trieste, Italy, May 20–22, 1999

Timothy K. Maclachlan, Raymond D. Meng, Wafik S. El-Deiry

Journal:

Journal of Cellular Physiology

Year:

1999

Language:

english

File:

PDF, 100 KB

english, 1999

9

Generation of Site-Directed Mutagenesis by Extralong, High-Fidelity Polymerase Chain Reaction

Nianli Sang, Gianluigi Condorelli, Antonio De Luca, Timothy K. MacLachlan, Antonio Giordano

Journal:

Analytical Biochemistry

Year:

1996

Language:

english

File:

PDF, 87 KB

english, 1996

10

10.1038/82119

MacLachlan, Timothy K., El-Deiry, Wafik S.

Journal:

Nature Medicine

Year:

2000

Language:

english

File:

PDF, 89 KB

english, 2000

11

BRCA1 signals ARF-dependent stabilization and coactivation of p53

Somasundaram, Kumaravel, MacLachlan, Timothy K, Burns, Timothy F, Sgagias, Magda, Cowan, Kenneth H, Weber, Barbara L, El-Deiry, Wafik S

Journal:

Year:

1999

Language:

english

File:

PDF, 790 KB

english, 1999

12

Comparative Gene Expression Profiling in Response to p53 in a Human Lung Cancer Cell Line

Suisui Song, Timothy K. MacLachlan, Raymond D. Meng, Wafik S. El-Deiry

Journal:

Biochemical and Biophysical Research Communications

Year:

1999

Language:

english

File:

PDF, 397 KB

english, 1999

13

Long-term study of antibody response and injection-site effects of oil adjuvants in Atlantic halibut (Hippoglossus hippoglossus L.)

Timothy J Bowden, Katy Adamson, Philip MacLachlan, Campbell C Pert, Ian R Bricknell

Journal:

Fish & Shellfish Immunology

Year:

2003

Language:

english

File:

PDF, 79 KB

english, 2003

14

A Rotaxane Exciplex

MacLachlan, Mark J., Rose, Aimee, Swager, Timothy M.

Journal:

Journal of the American Chemical Society

Year:

2001

Language:

english

File:

PDF, 62 KB

english, 2001

15

Rotaxanated Conjugated Sensory Polymers

Kwan, Phoebe H., MacLachlan, Mark J., Swager, Timothy M.

Journal:

Journal of the American Chemical Society

Year:

2004

Language:

english

File:

PDF, 70 KB

english, 2004

16

Preclinical Safety Evaluation of AAV2-sFLT01— A Gene Therapy for Age-related Macular Degeneration

MacLachlan, Timothy K, Lukason, Michael, Collins, Margaret, Munger, Robert, Isenberger, Elisabete, Rogers, Cindy, Malatos, Shana, DuFresne, Elizabeth, Morris, James, Calcedo, Roberto, Veres, Gabor, Sc

Journal:

Molecular Therapy

Year:

2011

Language:

english

File:

PDF, 435 KB

english, 2011

17

Storm forecasting: additional lessons from the CD28 superagonist TGN1412 trial

Horvath, Christopher, Andrews, Laura, Baumann, Andreas, Black, Lauren, Blanset, Diann, Cavagnaro, Joy, Hastings, Kenneth L., Hutto, David L., MacLachlan, Timothy K., Milton, Mark, Reynolds, Theresa, R

Journal:

Nature Reviews Immunology

Year:

2012

Language:

english

File:

PDF, 53 KB

english, 2012

18

Not Reinventing the Wheel: Applying the 3Rs Concepts to Viral Vector Gene Therapy Biodistribution Studies

MacLachlan, Timothy K., McIntyre, Maritza, Mitrophanous, Kyriacos, Miskin, James, Jolly, Douglas J., Cavagnaro, Joy A.

Journal:

Human Gene Therapy Clinical Development

Year:

2013

Language:

english

File:

PDF, 98 KB

english, 2013

19

Nonclinical Development of Novel Biologics, Biosimilars, Vaccines and Specialty Biologics || Turning the Corner with Viral-based Gene Therapy—Development of the Rogue Biopharmaceutical

MacLachlan, Timothy K.

Year:

2013

Language:

english

File:

PDF, 825 KB

english, 2013

20

Insulin-like growth factor binding protein-2 is a novel mediator of p53 inhibition of insulin-like growth factor signaling

Grimberg, Adda, Coleman, Carrie M, Shi, Zonggao, Burns, Timothy F, MacLachlan, Timothy, Wang, Wenge, El-Deiry, Wafik S.

Journal:

Cancer Biology & Therapy

Year:

2006

Language:

english

File:

PDF, 779 KB

english, 2006

21

In Vino, Curationis?

MacLachlan, Timothy

Journal:

Cancer Biology & Therapy

Year:

2008

Language:

english

File:

PDF, 758 KB

english, 2008

22

BRCA1 Transcriptionally Regulates Damaged DNA Binding Protein (DDB2) In the DNA Repair Response Following UV-Irradiation

Takimoto, Rishu, MacLachlan, Timothy K., Dicker, David T., Niitsu, Yoshiro, Mori, Toshio, El-Deiry, Wafik S.

Journal:

Cancer Biology & Therapy

Year:

2002

Language:

english

File:

PDF, 871 KB

english, 2002

23

Insights into differential endostatin activity

MacLachlan, Timothy K., Dhanabal, Mohanraj

Journal:

Cancer Biology & Therapy

Year:

2004

Language:

english

File:

PDF, 471 KB

english, 2004

24

Marine-derived cancer therapeutics making a splash

MacLachlan, Timothy K., Pinkas, Jan

Journal:

Cancer Biology & Therapy

Year:

2005

Language:

english

File:

PDF, 407 KB

english, 2005

25

Derisking Drug-Induced Carcinogenicity for Novel Therapeutics

Moggs, Jonathan G., MacLachlan, Timothy, Martus, Hans-Joerg, Bentley, Philip

Journal:

Trends in Cancer

Year:

2016

Language:

english

File:

PDF, 2.02 MB

english, 2016

26

Inflammation and immunogenicity limit the utility of the rabbit as a nonclinical species for ocular biologic therapeutics

de Zafra, Christina L.Zuch, Sasseville, Vito G., Matsumoto, Steven, Freichel, Christian, Milton, Mark, MacLachlan, Timothy K., Farman, Cindy, Raymond, Iona, Gupta, Swati, Newton, Ronald, Atzpodien, El

Journal:

Regulatory Toxicology and Pharmacology

Year:

2017

Language:

english

File:

PDF, 1015 KB

english, 2017

27

Corrigendum to “Inflammation and immunogenicity limit the utility of the rabbit as a nonclinical species for ocular biologic therapeutics” [Regul. Toxicol. Pharmacol. (2017) 221–230]

de Zafra, Christina L.Zuch, Sasseville, Vito G., Matsumoto, Steven, Freichel, Christian, Milton, Mark, MacLachlan, Timothy K., Farman, Cindy, Raymond, Iona, Gupta, Swati, Newton, Ronald, Atzpodien, El

Journal:

Regulatory Toxicology and Pharmacology

Year:

2017

Language:

english

File:

PDF, 126 KB

english, 2017

28

Computing equilibrium states of cholesteric liquid crystals in elliptical channels with deflation algorithms

Emerson, David B., Farrell, Patrick E., Adler, James H., MacLachlan, Scott P., Atherton, Timothy J.

Journal:

Liquid Crystals

Year:

2017

Language:

english

File:

PDF, 2.87 MB

english, 2017

29

Nonclinical Safety Evaluation of scAAV8- RLBP1 for Treatment of RLBP1 Retinitis Pigmentosa

MacLachlan, Timothy K., Milton, Mark N., Turner, Oliver, Tukov, Francis, Choi, Vivian W., Penraat, Jan, Delmotte, Marie-Hélène, Michaut, Lydia, Jaffee, Bruce D., Bigelow, Chad E.

Journal:

Molecular Therapy — Methods & Clinical Development

Year:

2018

Language:

english

File:

PDF, 2.70 MB

english, 2018

30

Cyclins, Cyclin-Dependent Kinases and Cdk Inhibitors: Implications in Cell Cycle Control and Cancer

MacLachlan, Timothy K., Sang, Nianli, Giordano, Antonio

Journal:

Critical Reviews in Eukaryotic Gene Expression

Year:

1995

File:

PDF, 4.67 MB

1995

31

Adherence in chronic hepatitis B: associations between medication possession ratio and adverse viral outcomes

Allard, Nicole L., MacLachlan, Jennifer H., Dev, Anouk, Dwyer, James, Srivatsa, Geeta, Spelman, Timothy, Thompson, Alexander J., Cowie, Benjamin C.

Journal:

BMC Gastroenterology

Year:

2020

File:

PDF, 623 KB

2020

32

Nonclinical Studies that Support Viral Vector-Delivered Gene Therapies: An EFPIA Gene Therapy Working Group Perspective

Bolt, Michael W., Whiteley, Laurence O., Lynch, Jessica L., Lauritzen, Brian, FernÃ¡ndez de Henestrosa, Antonio R., MacLachlan, Timothy, Ulrich, Peter, Philip, Binu K., Mahalingaiah, Prathap Kumar, Fu

Journal:

Molecular Therapy — Methods & Clinical Development

Year:

2020

File:

PDF, 39 KB

2020